Neuromechanical assessment of knee joint instability during perturbed gait in patients with knee osteoarthritis

Knee joint instability is frequently reported by patients with knee osteoarthritis (KOA). Objective metrics to assess are lacking, making it difficult target therapies aiming improve stability. Therefore, the aim of this study was compare responses in neuromechanics perturbations during gait self-reported (KOA-I) versus reporting stable knees (KOA-S) and healthy control subjects. Forty (20 KOA-I 20 KOA-S) controls were measured perturbed treadmill walking. angles muscle activation patterns compared using statistical parametric mapping discrete parameters. Furthermore, subgroups (moderate severe KOA) based on Kellgren Lawrence classification evaluated. Patients generally had greater flexion terminal stance swing gait. In response deceleration moderate increased their pre-swing. overall similar between groups. sway medial co-contraction quadriceps hamstrings muscles stance. respond different increasing angles, or both These alterations could assist assessment patients, provide treatment options accordingly. longitudinal studies needed investigate consequences altered due development KOA.